The area was populated with coppersmiths in the Middle Ages before later becoming home to a number of merchants and bankers.
According to Stow,[2] the street was: possessed for the most part by founders that cast candlesticks, chafing dishes, spice mortars, and such-like copper or laton works, and do afterwards turn them with the foot and not with the wheel, to make them smooth and bright with turning and scratching (as some do term it), making a loathsome noise to the by-passers that have not been used to the like, and therefore by them disdainfully called Lothberie.Lothbury was the location of the Whalebone, a meeting place for the radical Leveller movement in the mid seventeenth-century.
The nearest mainline railway station is Liverpool Street, with National Rail services towards East Anglia.
Lothbury borders the Bank on the building's northern side, and some of Sir John Soane's work dating from 1788 can still be seen there today.
41 Lothbury is a particularly noteworthy office building, designed by architects Mewes and Davis, with interior columns, marble walls and floor.