Louise of Savoy (28 December 1461 – 24 July 1503) was a member of the French royal family, who gave up a life of privilege and comfort to become a Poor Clare nun.

Louise was born on 28 December 1461, the Feast of the Holy Innocents, to the Amadeus IX, Duke of Savoy, and his wife, Yolande of Valois, the sister of King Louis XI of France.

While still a child, she was found to be fasting on only bread and water on the Vigil of any major feast day of the Blessed Virgin Mary.

Her uncle, the King, however, arranged that she marry on 24 August 1479 to Hugues de Chalon, (d.3 Jul 1490) of the House of Chalon-Arlay, to which she was agreeable.

The Prince proved to be a pious young man who supported his wife's efforts at living a life of faith and self-denial in the midst of their luxuries.