[1] The Lowell Museum was housed on the upper floors of a building on Merrimack Street at the head of Central Street[2] owned by Lowell's U.S. Postmaster, Fisher Ames Hildreth, and the theatre venue of the museum was managed by N. F. Gates.

A bayonet accidentally wounded an actor called Wheeler above the eye during one of the performances on the evening of May 26, 1853, killing him instantly in front of a packed audience.

[3] In the mid-1850s, local artist Alfred Ordway was commissioned to paint portraits of all the presidents to adorn the museum.

According to the January 31, 1856 New York Times article, The Lowell Museum was destroyed by fire, at a loss of $15,000, which was partially insured.

Randall & Co. clothing store, and the Law Library of Benjamin Butler next door.