Luca Valzania (born 5 March 1996) is an Italian professional footballer who plays as a central midfielder for Serie C Group B club Pescara.

On 13 May 2014 he made his professional debut for Cesena in Serie B as a substitute replacing Moro Alhassan in the 76th minute of a 1–0 home win over Empoli.

On 6 January 2015, Valzania made his Serie A debut in a 4–1 home defeat against Napoli, he was replaced by Massimo Volta in the 79th minute.

[5] On 9 August, Valzania made his debut for Cesena in a 4–0 home win over Lecce in the second round of Coppa Italia, he played the entire match.

[11] On 7 August he made his debut for Cittadella as a substitute replacing Lucas Chiaretti in the 79th minute of a 2–1 home defeat, after extra-time, against Cremonese in the second round of Coppa Italia.

[16][17] On 12 August he made his debut for Pescara as a substitute replacing Christian Capone in the 59th minute of a 3–1 away win over Brescia in the third round of Coppa Italia.

[18] On 3 September, Valzania made his Serie B debut for Pescara as a substitute replacing Mamadou Coulibaly in the 65th minute of a 4–2 away defeat against Perugia.

[34] On 30 August 2024, Valzania returned to Pescara in Serie C.[35] On 10 October 2017 he made his debut with Italy U21 team as a substitute replacing Alessandro Murgia in the 82nd of a 4–0 home win over Marocco U-20 in an international friendly.