Lucasville is a census-designated place (CDP) in Scioto County, Ohio, United States.

Lucasville was laid out by Captain John Lucas (1788-1825) in 1819, and named for him.

John volunteered for service and commanded a regiment during the War of 1812.

Upon the death of his father in 1814, John inherited much of his family's property in Scioto County, and it was on a portion of this land that he would establish the town of Lucasville on August 7, 1819.

He and his wife, Mary Lucas, ran a tavern in Lucasville until his death in 1825.

21.2% of all households were made up of individuals, and 10.4% had someone living alone who was 65 years of age or older.