[3] Ortiz spent the 2021 season with the Single–A Bradenton Marauders, making 22 appearances (19 starts) and recording a 3.09 ERA with 113 strikeouts in 87+1⁄3 innings of work.

[8] Pirates general manager Ben Cherington told the press that the club intended to use the remainder of the season to assess the quality of starting pitching in their organization.

[9] Ortiz made 4 starts during his rookie campaign, posting an 0–2 record and 4.50 ERA with 17 strikeouts over 16 innings of work.

[11] Ortiz made 37 appearances (15 starts) for the Pirates in 2024, accumulating a 7–6 record and 3.32 ERA with 107 strikeouts and 1 saves across 135+2⁄3 innings pitched.

[12] On December 10, 2024, Ortiz, alongside Michael Kennedy and Josh Hartle, was traded to the Cleveland Guardians in exchange for Spencer Horwitz.