In the first story arc of the series, he infiltrates a data center to steal digital currency from "Marco Polo", a site on the dark web, which sells illegal items such as drugs and weapons.

In the third story arc, Lupin intends to steal the Bloody Teardrop, a national treasure of the Southeast Asian kingdom of Padar, which is currently worn by its royal princess Dolma, who has befriended Ami.

Recurring subthemes in the series include the use of contemporary high technology (particularly the Internet, facial recognition programs and surveillance drones), and the question of trust between Lupin and the rest of his gang.

It was written by Ichirō Ōkouchi alongside Gō Zappa, Daisuke Sakō, Kazushige Nojima, Takahiro Okura, Yuniko Ayana, Keiichi Sigsawa and Shatner Nishida,[4] and featured character designs by Hisao Yokobori.

Its title is a reference to the debut episode of the first Lupin the Third anime series and follows its story, but features other enemies such as Kyosuke Mamo, Sandayu Momochi, Pycal, and Stoneman.