Various lysophosphatidylserines trigger TLR 2.
[2] They can also trigger mast cell degranulation.
[3] They interact with three G protein-coupled receptors (GPCRs), LPS1/GPR34, LPS2/P2Y10, and LPS3/GPR174.
[2] A recent study showed that lysophosphatidylserines do not stimulate normal leukocytes.
[4] They also enhances glucose transport, lowering blood glucose levels while leaving secretion of insulin unaffected.