The M10 road is a long metropolitan route in the City of Tshwane in Gauteng, South Africa.

It then heads eastwards to pass under the N14 highway (Ben Schoeman Freeway) and enter the suburb of Lyttelton, where it meets the M18 route (Botha Avenue) and passes through as Trichardt Avenue.

[5] The M10 continues eastwards as Solomon Mahlangu Drive (formerly Hans Strijdom Drive[6]) to bypass the Air Force Base Waterkloof and meet the R21 highway at Monument Park in Pretoria.

[5] Still named Solomon Mahlangu Drive, the M10 heads north-east to cross the N4 toll highway (Maputo Corridor) east of Equestria before meeting the R104 route (Bronkhorstspruit Road) at the next junction.

From the R104 junction, it continues north-east for 10 km, entering and passing through the large township of Mamelodi.