The force field applies a mapping of four heavy atoms to one CG interaction site and is parametrized with the aim of reproducing thermodynamic properties.
[3] For the Martini force field 4 bead categories have been defined: Q (charged), P (polar), N (nonpolar), and C (apolar).
[7] The initial papers[1][2] contained parameters for water, simple alkanes, organic solvents, surfactants, a wide range of lipids and cholesterol.
[8] Compatible parameters for proteins were introduced by Monticelli et al..[9] Secondary structure elements, like alpha helixes and beta sheets (β-sheets), are constrained.
[14] Parameters for different other molecules, including carbon nanoparticles,[15] ionic liquids,[16] and a number of polymers,[17][18][19] are available from the Martini website.