[3][4] After graduating from medical school, Seagrave spent 18 months as the house physician at the New York Infirmary for Women and Children before returning to Seattle.

[5][6] In 1918, Seagrave and her Wellesley friend, Florence Denny Heliker, were sent to France by the National American Woman Suffrage Association.

[7][8][9] The Women’s Oversea Hospitals, U.S.A., which sent 78 female physicians to Europe during the war, saved countless lives, Seagrave told The Seattle Daily Times when she arrived back home in 1919.

Military surgery in France today is of the greatest educational value, and an opportunity all surgeons must covet."

After the Armistice of 11 November 1918, Seagrave worked at a Red Cross hospital at Foug, in northeastern France—the Western Front during the war.

The King County Medical Bulletin reported "a little chat with her was to get a sunnier slant on life."

“For a year I tried to go on living at my old home, but it was too lonesome,” she told the Johns Hopkins alumni bulletin.

She rented out the house and moved in with a dear friend from Wellesley’s Class of 1909, Willye Anderson White, the widow of a prominent Seattle financier.

In a letter to their Wellesley friends, Willye White wrote that Seagrave gave away more money than anyone knew.