This was the nation's fifth consecutive appearance at the Summer Olympics in the post-Yugoslav era.

Marko Blaževski, medley swimmer and finance student at the Wingate University in North Carolina, was appointed by the Macedonian Olympic Committee to be the nation's flag bearer at the opening ceremony.

For the first time in Olympic history, Macedonia did not qualify athletes in freestyle wrestling, slalom canoeing, and shooting.

Macedonia failed for the third consecutive time to win an Olympic medal.

Macedonian athletes received wild cards for both men's and women's 400 metres.