Mackenziidae is a family of enigmatic animals known from the Cambrian period.

Their affinity has been disputed, with the type genus Mackenzia being first described as a holothurian echinoderm,[1] before being moved to a relative of sea anemones,[2] and finally in 2022 moved to Eumetazoa incertae sedis.

[3] The family may be related to various members of the Ediacaran biota, due to a similar arrangement of tubular modules.

[3]