Madagascar competed at the 2012 Summer Olympics in London, United Kingdom from 27 July to 12 August 2012.

Comité Olympique Malgache sent a total of 7 athletes to the Games, 3 men and 4 women, to compete in 5 sports.

For the second time in Olympic history, Madagascar was represented by more female than male athletes.

Judoka and Olympic qualifier Fetra Ratsimiziva was the nation's flag bearer at the opening ceremony.

Among the five sports played by the athletes, Madagascar also marked its Olympic debut in freestyle wrestling.