Over the years, Madame Masque has appeared in various forms of media, including animated television series and video games.

A version of Whitney Frost appears in the second season of the Agent Carter television series set in the Marvel Cinematic Universe, portrayed by Wynn Everett.

Whitney Frost first appeared in Tales of Suspense #97 (October 1967) using the code name Big M and was created by Stan Lee and Gene Colan.

Following the Frosts' deaths, Count Nefaria approached Whitney and revealed her true parentage, as he wishes for her to inherit his position as head of the Maggia, a Mafia-like organization based on the East Coast of the United States.

Heartbroken, Whitney accepted her father's offer to join the Maggia and was trained by the Count in strategy, criminal activities, and combat.

The plane she escaped in crashed and Whitney's face was badly scarred, but she was saved by the criminal Mordecai Midas and started to work for him.

"[7] Madame Masque meets Tony Stark (Iron Man's alter ego) and the latter shows concern for her despite her scarred face.

Whitney is unable to choose between her father and her lover, and when Nefaria's life-support system is damaged in the fight, she goes insane with guilt and grief.

[10] She also creates robotic servants known as the Inner Guard and names them individually after notable historical traitors: Benedict, Brutus, Fawkes, Quisling, Monmouth (based on Benedict Arnold, Marcus Junius Brutus, Guy Fawkes, Vidkun Quisling, and the Duke of Monmouth) and two other, unnamed members.

[volume & issue needed] Masque again tries unsuccessfully to convince her to side with the heroes, then joins the battle in Whitney's place.

Whitney joins the battle and plays a key role in her father's defeat, her weapon causing him to begin leaking ionic energy until he finally collapses.

[13] Madame Masque is hired by the Hood to take advantage of the split in the superhero community caused by the Superhuman Registration Act.

[24] Later, when The Hood attacks Doctor Strange in order to become the Sorcerer Supreme, she tries to help him deal with his possession by Dormammu, taking off her mask and confessing her feelings for him.

[29] During the "Heroic Age" storyline, Hood escapes from prison and makes a play to assemble the Infinity Gauntlet, for which he recruits Masque.

[33] In the pages of "Avengers Undercover" Madame Masque appears as a member of the Shadow Council's Masters of Evil in Bagalia.

[36] Upon traveling to Mary Jane Watson's nightclub, Jackpot, in Chicago, Madame Masque confronts her former business partner Belhilio and kills him.

A furious Watson hits her in the face with a microphone, knocking her mask off, and Doctor Doom discovers that Madame Masque has been demonically possessed.

By the time Iron Man regains consciousness, Doctor Strange arrives and informs him that he will take Madame Masque away to metaphysically fix her and will later hand her over to the custody of S.H.I.E.L.D.

[40] Madame Masque is among the crime lords competing with Mister Negative in obtaining the Tablet of Life and Destiny to win the favor of Mayor Wilson Fisk.

As leader of the Maggia family, Madame Masque commands unspecified numbers of Dreadnought robots modified from the original designs stolen from HYDRA.

Madame Masque wears body armor of an unknown composition with a gold metal faceplate, underneath which her face was chemically scarred.

She carries a .475 Wildey Magnum revolver and other handguns, in addition to weapons that fire concussive blasts of energy or sleeping-gas cartridges.