Madhouse is a 2004 American slasher film, directed and co-written by William Butler and starring Joshua Leonard, Jordan Ladd, Natasha Lyonne, Lance Henriksen, and Mark Holton.

Years later, psychiatric intern Clark Stevens arrives to Cunningham Hall to train before he can graduate to medical school.

Inside, he meets some of the patients and is welcomed by Nurse Betty, who gives him keys and a walkie-talkie before taking him to the director of the facility, Dr. Albert Franks.

Sara talks privately with head nurse Annabelle Hendricks before finishing the tour with the basement cells, where the most dangerous patients are kept—a place nicknamed "Madhouse."

Clark sees the boy again and pursues him to the Madhouse but only finds Dr. Morton, who recalls a patient from Cell #44 who escaped but apparently died.

Hendricks, equipped with her stun-gun, investigates the source and is attacked by a cloaked figure who kills her by electrocuting her with a defibrillator.

Sometime later, Clark attempts to confront Sara with some questions about the facility but is unable due to a nurse discovering Carl has hung himself.

Taking Ben's advice, Clark discovers that Franks has been using placebos on patients and embezzling the hospital's funding.

When Madhouse eventually runs out of tape and cinematic scraps to work from the writer (in this case, the director too) panics and resorts to a weak twist ending, a desperate last gasp that only backfires on the film and every story point to come before it.