The Makedonia Palace (Greek: Μακεδονία Παλλάς) is a 5-star hotel located in Downtown Thessaloniki, Greece.

Every September, during the annual opening ceremony of the Thessaloniki International Fair, the Prime Minister of Greece stays at Makedonia Palace along with most of the Cabinet.

[7] The hotel has also hosted many Greek and international celebrities, including Russian president Vladimir Putin,XIKI,Chuck Norris, Faye Dunaway, Colin Farrell and Catherine Deneuve, during their stay in the city.

[7] In 2014, Belterra Investments, owned by Ivan Savvidis, leased the hotel through a 30-year contract, at a €1.7 million annual rent.

[8][9] The building is a landmark at Thessalonikis' new seafront (Nea Paralia), remodelled in exemplary manner by Nikiforidis - Cuomo Architects.