He played his entire NFL career with San Diego after signing with them as an undrafted free agent in 2004.

He was signed by the San Diego Chargers as an undrafted free agent after the 2004 NFL draft.

In 2004, Floyd was signed by the San Diego Chargers as an undrafted rookie soon after the draft on April 30.

He was waived on September 5 and signed to the practice squad two days later, and then re-signed to the active roster on December 11.

In 2006, Floyd caught a 31-yard touchdown pass against the Baltimore Ravens, on a play in which Samari Rolle slipped and fell in coverage.

He caught a touchdown pass for the second time in two weeks with a nine-yard tip-toe catch in the back corner of the end zone against Pittsburgh.

He was selected as the Chargers Alumni Player of the Week following the game in Cincinnati, after substituting for Eric Parker who was out with a neck injury.

In 2007, Floyd made a 25-yard catch on a 3rd-and-13 play during the opening drive of the second half against Green Bay Packers that helped set up 21-yard touchdown catch-and-run by LaDainian Tomlinson.

He helped extend the Chargers' touchdown drive on the opening series of the Week 6 game against the Oakland Raiders with a 16-yard catch on 3rd down.

After the end of the 2011 NFL Lockout, Floyd was courted by the Ravens before re-signing for two years with the San Diego Chargers on August 5.

Only Henry Ellard, who totaled 71 first downs on 74 catches (95.9%) for the Washington Redskins in 1994, posted a higher percentage.

[7][8] On September 15, 2013, during a Week 2 game against the Philadelphia Eagles, Floyd was again carted off the field after an undisclosed head injury.

[9] He had 52 catches and six touchdowns; his receiving yards (856) tied his career high and also led the team for the second time in three years.