Mike Anderson and Trevor Pryce were both waived due to salary cap issues and were subsequently picked up by the Baltimore Ravens.
In addition to their regular home-and-away series with AFC West rivals the Raiders, the Chiefs and the Chargers, the Broncos played teams from the AFC North and NFC West as per the schedule rotation established in 2002,[1] and also played intraconference games against the New England Patriots and the Indianapolis Colts based on their common divisional position vis-à-vis the Broncos from 2005. at the Edward Jones Dome, St. Louis, Missouri The Broncos opened the regular season on the road against the St. Louis Rams on September 10 in the Edward Jones Dome.
Rookie Mike Bell ran for 58 yards and scored the only touchdown in the entire game late in the second quarter on a 1-yard run.
The Broncos scored a 23-yard field goal (by kicker Jason Elam) and a touchdown in the second quarter (a 32-yard TD pass from QB Jake Plummer to Javon Walker).
The Broncos had a bye week, but moved into a first place tie in the division when the San Diego Chargers lost to the Baltimore Ravens 16–13.
The Broncos controlled the clock in the second half with the running game led by Tatum Bell, who atoned for his fumble in the first quarter by bouncing back with 92 yards rushing.
Ravens QB McNair was intercepted again by Darrent Williams, which led to a Jake Plummer to Rod Smith touchdown pass.
Oakland had two turnovers deep in Broncos territory, one an interception thrown by Andrew Walter that was picked off by Champ Bailey, and another a fumble by LaMont Jordan.
Jason Elam succeeded on kicks from 51 and 22 yards, while Sebastian Janikowski scored the only points for Oakland on a 47-yard field goal in the third quarter.
The only turnover of the game came on a Jake Plummer fumble on the next drive by the Broncos, leading to another easy touchdown pass to Wayne, putting the Colts ahead 17–14.
The 37-yard field goal by Vinatieri with 2 seconds left won the game for the Colts, breaking the tie and allowing them to remain undefeated.
Denver's powerful run attack (currently third in the league behind the Atlanta Falcons and San Diego Chargers) gained 227 yards against the league-worst Colts run defense (including 136 by rookie Mike Bell), but it simply wasn't enough to counter the Colts' powerful offense (which also ran for 93 yards, all by rookie Joseph Addai, a career-high).
Denver again moved into a first place tie in the AFC West with the San Diego Chargers as they won their game against the St. Louis Rams.
The Broncos got on the scoreboard quick with Jake Plummer throwing a 16-yard touchdown strike to WR Rod Smith on their first drive of the game.
On the next drive, the Steelers got to the Denver 41-yard line when QB Ben Roethlisberger completed a 35-yard pass to WR Cedrick Wilson, who then fumbled the ball and the Broncos recovered.
at Invesco Field at Mile High, Denver, Colorado Following their season sweep over the Raiders, the Broncos went home for a Sunday night match-up with their AFC West rival, San Diego Chargers.
In the third quarter, kicker Jason Elam completed a 42-yard field goal, while CB Darrent Williams returned an interception 31 yards for a touchdown.
In the third quarter, Tynes helped the Chiefs get a 34-yard field goal, while Plummer completed a 1-yard TD pass to TE Stephen Alexander.
at Invesco Field at Mile High, Denver, Colorado Trying to break a two-game losing streak, the Broncos went home for a Sunday night fight with the Seattle Seahawks.
After a scoreless third quarter, Seattle took control of the game with RB Shaun Alexander's 1-yard TD run, along with kicker Josh Brown's 44-yard and 23-yard field goal.
However, Denver's defense couldn't hold off the Seahawks' response, as Brown nailed a 50-yard field goal, spoiling Cutler's debut.
at University of Phoenix Stadium, Glendale, Arizona Broncos' fans were given several reasons to hope for the future during this road win against the similarly rookie quarterback-led Cardinals.
Playoff Implications: Jay Cutler replacing Jake Plummer for his third regular-season start had an impressive game with 21 completions on 31 attempts for 261 yards total.
The win in Arizona kept the Broncos' playoff hopes alive and set up an exciting must-win situation against the Cincinnati Bengals in week 16.
at Invesco Field at Mile High, Denver, Colorado Following their road victory over the Cardinals, the Broncos went home for a snowy Christmas Eve fight with the Cincinnati Bengals.
However, Cincinnati responded with kicker Shayne Graham's 46-yard field goal and QB Carson Palmer's 11-yard TD pass to WR Chris Henry.
In the second half, the Broncos took the lead with RB Mike Bell's 2-yard TD run in the third quarter and kicker Jason Elam's 24-yard field goal.
Denver looked strong early and led the visiting 49ers 13–3 at halftime, but San Francisco used a stingy goal-line defense and a heavy dose of NFC rushing champ Frank Gore to take a lead late into the second half.
The overtime period consisted of classic field-position football, with San Francisco steadily gaining field position but losing the battle with the clock.
On New Year's Day 2007, less than 12 hours after the last game ended, second-year cornerback Darrent Williams was shot and killed in a drive-by shooting.