It stars Sofia Andres,[3] Diego Loyzaga, Jameson Blake,[4] Sylvia Sanchez,[5] Yana Asistio, Heaven Peralejo, Karen Reyes, Arlene Muhlach, Alora Sasam and Afi Africa, among others.

In line with the theme of the film, director Connie Macatuno and most of the cast who attended the event walked the red carpet with their mothers.

[8] Pablo Tariman of The Philippine Star praised Macatuno's directing, noting how she delivered "with simple storytelling that hit the emotional mark without fanfare" and also Sylvia Sanchez's performance as compared to her other roles as mother on TV.

[9] Rappler's Oggs Cruz wrote, "Mama's Girl is hardly a perfect film but its subtle but sincere impressions are worth the price of the ticket".

He called to attention an apparent lack of influence of men on the main characters and their development, while comparing it to Macatuno's previous film Rome and Juliet, saying that it was "definitely softer" than its predecessor.