Mana Khemia: Alchemists of Al-Revis[a] is a role-playing video game developed by Gust Co. Ltd. in 2007 for the PlayStation 2.

The game is the ninth entry to Gust's Atelier series and incorporates elements of standard turn-based combat and alchemy.

Mana Khemia shares many common elements with its predecessors, the Atelier Iris trilogy.

At the core of the game is alchemy through which the player can create weapons, armor, usable items, and complex ingredients for these recipes.

The player is required to gather core materials through field exploration, spoils of combat, or by purchasing them in the shops.

Each item carries fundamental properties that include elemental and special abilities, and character stat improvements, that can be infused into equipment.

A new "alchemy wheel" allows the player to adjust the quality of each ingredient as it is added to the mix, for better or worse, in order to alter the final item's properties as well.

When in the field, the player can opt to avoid encounters with monsters by running and jumping over them, but also may attempt to strike first to go into battle.

Mana Khemia uses a turn-based system similar to previous Atelier Iris games.

Unlike typical role-playing games, there are no experience points or characters levels.

However, these bonuses are tied to completing the recipes for specific items in that book.

Each term is made up of several weeks, typically starting and ending with an event, ultimately leading to a key battle to be won.

If the player should fail to make a decent cumulative grade by the end of courses, they will need to spend one day of free time in detention, doing required tasks.

Since then, Vayne has led the life of a hermit, his only companion being a Mana in cat form named Sulpher.

Vayne is invited to the Al-Revis Academy for alchemy training by Zeppel, one of the professors.

He is quickly indoctrinated into the school by becoming part of an atelier led by Flay Gunnar (an older student who is known as The Defender of Justice) along with two other students, Jess (a clumsy girl who is nevertheless adept at alchemy), and Nikki (an impulsive beastgirl).

They are soon joined by Pamela (the school's resident ghost), Anna (an 11-year-old master swordsman), Roxis (the son of a famous family of alchemists who is quickly forced to join the workshop by Flay), and Muppy (an alien the group discovers on an assignment).

The eight of them are able to succeed at completing assignments, learn the skills of alchemy, and allow the workshop to prosper.

The soundtrack was composed by Ken Nakagawa and Daisuke Achiwa and includes opening song "Run For Your Life"' by Haruka Shimotsuki and ending song "TOGGLE" by Yuuki Mizusawa.

[3] A port for the PSP system that was released in Japan on September 25, 2008 under the title Mana-Khemia Gakuen no Renkinjutsushi-tachi Portable Plus (マナケミア 〜学園の錬金術士たち〜 ポータブルプラス, Mana Kemia ~Gakuen no Renkinjutsushi-tachi~ Pōtaburu Purasu), and in North America on March 10, 2009, branded under the name Mana Khemia: Student Alliance.

There are added features like multiplayer battles, Jump Start function to allow the game to load faster, and more items that can be synthesized.

In multiplayer battles, enemies may drop rare items that cannot be found in the main game.

[13] This was due to its additional loading times, but this can be remedied by playing the download rather than the UMD or using the install function.

[24] Its story is set 15 years after the original game, and the only returning characters are Flay, Tony, and Zeppel.