She studied ancient Greek philosophy and history at a college in Trieste, and spoke French, Italian and Turkish fluently.

She equipped, manned and "privateered" at her own expense, two ships with which she pursued the pirates who attacked Mykonos and other islands of Cyclades.

Later, Mavrogenous sent another corps of fifty men to Peloponnese, who took part in the Siege of Tripolitsa and the fall of the town to the Greek rebels.

She later put together a fleet of six ships and an infantry consisting of sixteen companies, with fifty men each, and took part in the battle in Karystos in 1822, and funded a campaign to Chios, but she did not prevent it from the massacre.

When the Ottoman fleet appeared in Cyclades, she returned to Tinos and sold some of her jewelry to finance the equipment of 200 men who fought the enemy and cherish two thousand people who had survived from the first siege of Missolonghi.

After Ypsilanti's death and her intense political conflicts with Ioannis Kolettis, she was exiled from Nafplio and returned to Mykonos, where she occupied with the writing of her memoirs.

When the war ended Ioannis Kapodistrias awarded her the rank of the Lieutenant General and granted her a dwelling in Nafplio, where she moved.

The home is located near the Panagia Ekatontapyliani (the Church of the Virgin Mary) which, tradition says, was founded by Saint Helena, mother of Constantine the Great.