Manuel de Irujo Ollo (25 September 1891 – 1 January 1981) was a lawyer and politician from Navarre, Spain, who became the leader of the Basque Nationalist Party during the Second Spanish Republic.

He was the son of the lawyer Daniel Irujo y Urra, professor in the University of Deusto and a Navarre nationalist.

[2] His maternal grandmother was born in the Philippines, daughter of the president of the Audencia of Manila, the high court of the territory.

He was reelected provincial deputy in 1923, but lost his seat that year with the dictatorship of Miguel Primo de Rivera, and was imprisoned for a period.

[1] On hearing of the military revolt in July 1936 at the start of the Spanish Civil War (1936–1939) Irujo and the nationalist deputy Lasarte delivered a note to the civil governor in which, on behalf of their parliamentary group, they invited the armed forces and civilians to assist the legitimate legal powers against the military fascist movement.

As one of the leaders of the loyalist forces, Irujo played a leading role in the negotiations that led to the surrender of the garrison of Loiola in San Sebastián.

[1] The PNV quickly assumed control of the Basque Country, but found themselves fighting both against the rebels and against members of the radical left, whom Irujo called "extremist elements brought into the house".

[6] On 5 September 1936 the PNV leader, José Antonio Aguirre, was offered the Ministry of Public Works in the new Republican government headed by Francisco Largo Caballero.

The PNV demanded immediate approval of the Basque Statute as a condition, and when this was agreed Irujo took office as Minister Without Portfolio on 26 September 1936.

[10] Irujo accepted the post on condition that the freedom of conscience was respected, as guaranteed by the constitution, that public worship was restored and that steps be taken to free imprisoned priests and members of religious orders.

This stance became hard to maintain when the episcopate's Collective Letter was circulated in August 1937, since it supported General Francisco Franco and apparently incited people to rebel against the Republic.

During World War II (1939–1945) he chaired the Basque National Council in London in 1941 in the absence of Aguirre, and signed an agreement with General Charles de Gaulle on the Europe of Tomorrow.

He proposed a constitution for a Basque Republic as a buffer state between a future liberated France and a reduced or confederated Spain, supposing that the Allies would defeat Franco.