Marduk has given me an heir) was a Chaldean leader from the Bit-Yakin tribe, originally established in the territory that once made the Sealand in southern Babylonia.

[2] He was known as one of the kings who maintained Babylonian independence in the face of Assyrian military supremacy for more than a decade.

Sargon of Assyria repressed the allies of Marduk-apla-iddina II in Elam, Aram and Israel and eventually drove him from Babylon (c. 710 BC).

After the death of Sargon, Marduk-apla-iddina II briefly recaptured the throne from a native Babylonian nobleman.

A cylinder of Marduk-apla-iddina II from Uruk describes his rebuilding of the temple of Ningishzida built by the Ur III ruler Shulgi alongside the ziggurat of E-Anna.