Vogt joined her parents at a private institute in Neustadt, the Black Forest, where the family lived for the duration of World War II; there, she worked extensively on Drosophila development.

They were the first to successfully grow the virus in vitro and were able to plaque purify it, an essential step for subsequent vaccine production.

[7] Dulbecco was recruited to the newly founded Salk Institute for Biological Studies in 1963, and Vogt joined him as a research fellow in his group.

[3] Her interests evolved to examining cellular immortalization in cancer cells, and the role of telomeres in this process.

Vogt made significant contributions as a scientist in multiple areas: as a Drosophila developmental geneticist, as a virologist working with Nobel laureate Renato Dulbecco, and as an investigator into viral transformation and cellular immortalization.