Maria Iandolo New (December 11, 1928 - July 26, 2024[1] [2] [3]) was a professor of Pediatrics, Genomics and Genetics at Icahn School of Medicine at Mount Sinai in New York City.

[citation needed] In 1964, New was appointed Chief of Pediatric Endocrinology at Cornell University Medical College, a position she held for 40 years.

In 2004, New was recruited to the Mount Sinai School of Medicine as Professor of Pediatrics and Human Genetics and Director of the Adrenal Steroid Disorders Program.

New's research on the mechanism and genetics of steroid disorders has established standards for pre- and post-natal care for patients with congenital adrenal hyperplasia and apparent mineralocorticoid excess.

[citation needed] During a 43-year period, New held the longest continuously funded National Institutes of Health grant, "Androgen Metabolism in Childhood", which supported research characterizing the diverse clinical spectra of patients with rare steroidogenic enzyme defects, such as congenital adrenal hyperplasia, and their metabolic consequences.

[10] Her team was the first to publish mutations on the 11β-hydroxysteroid dehydrogenase type 2 enzyme (encoded by the HSD11B2 gene) causing this potentially fatal form of low renin hypertension.

While a spectrum of severity of congenital adrenal hyperplasia had always been observed, New was first to identify the mild form with specific molecular mutations.