Maria Regina High School, commonly referred to as Maria or MRHS, is an American Catholic, college-preparatory high school (grades 9–12) for girls founded by the Sisters of the Resurrection, located in Hartsdale, New York.

The highest scorers who put Maria Regina as their first choice receive the scholarships.

There is a wide variety of electives to choose from for juniors and seniors, such as introduction to Law, 3D Printing, and Criminal Justice.

Leadership, service and spiritual: Extracurricular clubs : Publications Language and culture clubs: Performance Maria Regina High School is an active member in the Catholic High School Athletic Association.

All Maria Regina teams compete in non-conference tournaments, games, and matches so that the schedules are highly competitive.