The school began as the Ursuline Seminary for Girls in September 1897, operating out of Leland Castle at the now-closed College of New Rochelle.

As registration increased, a wing was added to the southern end of the castle and the College of New Rochelle was founded.

Seventh- and eighth-grade students have the opportunity to earn high school credit in a foreign language, mathematics, and science.

[3] Leadership, service and spiritual: Co-curricular clubs: Other activities: Publications: Language and culture clubs: Performance: The school belongs to the New York State Public High School Athletic Association, with 30 interscholastic teams in swimming, tennis, field hockey, soccer, volleyball, cross-country, cheer leading, basketball, softball, lacrosse, golf, and indoor and outdoor track.

Athletic facilities include a full-size gymnasium, a multi-sport playing field, and three tennis courts.