Shortly after he became a priest his superiors appointed him librarian at the monastery of St.-Germain-des-Prés, which at that time possessed a library of 60,000 books and 8,000 manuscripts.
Being well versed in ancient Greek, Bouquet assisted his confrère Bernard de Montfaucon in his edition of the works of John Chrysostom.
Bouquet's greatest work is his collection of the historians of Gaul and France, entitled: Rerum Gallicarum et Francicarum Scriptores.
The design was accepted and the Oratorian LeLong who had just finished his "Bibliothèque historique de la France" was entrusted with the task.
Bouquet was banished to the monastery of St.-Jean, at Laon, but in 1735, D'Aguesseau and a few other influential persons succeeded in having him recalled to Argenteuil, and afterwards to Blancs-Manteaux, where he could more easily supervise the publication of his work.
The greater part of the material for the ninth volume was ready when Bouquet died at the monastery of Blancs-Manteaux, in Paris.