Marycrest Girls High School was an all female high school located at 5320 Federal Boulevard in Denver, Colorado, United States.

[2] The Sisters of St. Francis of Penance and Christian Charity purchased property near 52nd Avenue and Federal Boulevard in northwest Denver to house a convent and motherhouse for their order's new midwestern province in 1938.

The sisters converted their novitiate into Marycrest High School in 1958.

[3] Following the school's closure, its campus was leased to Tennyson Center for Children with an option for that organization to purchase the property.

[4] In 1996, the building was demolished and replaced with assisted living residences.