[1] The neighborhoods of Abell, Cedarcroft, Charles Village, Coldstream-Homestead-Montebello, Ednor Gardens-Lakeside, Guilford, Homeland, Hillen, Lake Evesham, Lauraville, Mid-Govans, Northwood, Pen Lucy, Radnor-Winston, Ramblewood, Stonewood-Pentwood-Winston, Tuscany-Canterbury, Waverly, Wilson Park and Woodbourne Heights, Baltimore make up the majority of the district.

[citation needed] As of the 2020 United States census, the district had a population of 109,154, of whom 90,503 (82.9%) were of voting age.

[5] Several of Maryland's larger institutions of higher education are located within the 43rd district.

With the district being redrawn in 2012 per the 2010 census, most of the Johns Hopkins University Homewood campus is in the 43rd.

The 43rd district is also home to Baltimore City College, the oldest high school in Maryland.