Route 112 is a 54.11-mile-long (87.08 km) rural state highway through western Franklin and Hampshire Counties.

The route continues northward through town, passing the Knightville State Wildlife Management Area and the Hiram H. Fox State Wildlife Management Area before entering the town of Worthington.

The two routes pass concurrently along the river through the center of town before heading into Goshen, finally splitting near the Lower Highland Lake, where Route 112 turns northwards towards Ashfield.

From there, Route 112 follows the North River into the town of Colrain.

The section between Worthington and Cummington was also moved to the current route during this time period.