In 1997, Selman joined the writing staff of The Simpsons, where he has remained, rising to the position of executive producer.

[4] He has written or co-written 28 episodes of the show, including "Natural Born Kissers" which the show's creator Matt Groening listed as his eighth favorite episode in 2000,[5] "Behind the Laughter", "Trilogy of Error", "Sky Police" and "The Food Wife".

Selman has won six Primetime Emmy Awards for his work on the show, sharing them with the other producers.

Selman formerly wrote for Time.com's Techland "Nerd World" blog alongside Lev Grossman,[12] and is also the creator and writer of the Icebox.com webtoon "Superhero Roommate.

He appeared alongside Groening and voice actor Hank Azaria to judge on a The Simpsons-themed challenge on an episode of Top Chef: Masters in 2010.