[3] In 2023, he earned his degree in Marketing Management in University of San Jose–Recoletos through the Expanded Tertiary Education Equivalency and Accreditation Program (ETEEAP).

[6] Guidicelli's acting career started when he joined the fourth season of the teenage comedy sitcom Go Kada Go in 2007, becoming a member of ABS-CBN's Star Magic.

The next year, he played supporting roles in the action fantasy show Kung Fu Kids and in the soap opera Ligaw na Bulaklak.

He used to be a regular on SOP Fully Charged along with a guest role in All My Life as part of his transfer to GMA Network.

[8] He landed his first lead role in 2012, starring as the lovestruck Carlo in the successful indie film, My Cactus Heart.

[10] After almost 13 years, Guidicelli returned to GMA Network as he joined the longest-running morning show Unang Hirit.

[11] In November 2019, Matteo got engaged to his long time girlfriend Sarah Geronimo; they got secretly married in a Christian Wedding Ceremony at Victory Church, The Fort past six in the evening, Thursday night on February 20, 2020.