Maverick Junction (Lakota: Mniwóblu Oínažiŋ[2]), South Dakota, United States, is an unincorporated community and census-designated place (CDP) located in Fall River County at the intersection of South Dakota Highway 79 and US Highways 18 and 385, approximately five miles southeast of Hot Springs.

A variety of businesses have been built and operated at the location for many years including stores, restaurants and fuel stations.

SH-79 and US-18/385 south of Maverick Junction are part of the Heartland Expressway connecting the eastern side of the Black Hills with Alliance and Scottsbluff, Nebraska, and the Front Range of Colorado.

As of the Fall of 2009, the expressway has been completed as a dual-roadway four-lane highway from Rapid City, South Dakota to Maverick Junction, and the next segment south through Oelrichs to the Nebraska stateline, paid for by 19 million dollars in federal funding, plus matching state funds, is now under construction.

US-18/385 from Maverick Junction to Hot Springs (4.5 miles) is named the Leslie Jensen Memorial Highway in honor of South Dakota's 15th governor, and follows Fall River up the canyon of the same name to the tourist, veteran's services, market, and county town, known for its 1890s architecture and a variety of minor tourist attractions.