In 2003, under the guidance of L. S. Portnoy, he defended his thesis for the degree of candidate of economic sciences "Management of the region's economy on the basis of financial flows: principles and models (based on the example of the Perm Krai)" Prior to joining the Perm Krai administration, he worked at Sterlinggroup Forecast.

On 12 October 2009, he was appointed Director of the Department of Public Administration, Regional Development and Local Self-Government of the Apparatus of the Government of the Russian Federation, headed by Sergey Sobyanin.

From April 2012 to February 2017, Reshetnikov was the Minister of the Government of Moscow, head of the Department of Economic Policy and City Development.

On 6 February 2017, by decree of Russian President Vladimir Putin, he was temporarily appointed (until the election) as acting governor of the Perm Krai.

On December 8, 2018, on the basis of a decision adopted by delegates of the XVIII Congress of the United Russia, he was included in the Supreme Council of the party.

[5] [6] On 2 June 2022 the United States Department of the Treasury placed sanctions on him as a member of the Government of Russia pursuant to Executive Order 14024.