Mayadin District (Arabic: منطقة الميادين) is a district (mantiqah) administratively belonging to Deir ez-Zor Governorate, Syria.

At the 2004 official census, the district had a population of 247,171.

[2] Its administrative centre is the city of Mayadin.

The district of Mayadin is divided into three subdistricts or Nāḥiyas (population according to 2004 official census):

This article about a location in Deir ez-Zor Governorate, Syria is a stub.