Deir ez-Zor District (Arabic: منطقة دير الزور, romanized: manṭiqat Dair az-Zaur) is a district of the Deir ez-Zor Governorate in northeastern Syria.

The administrative centre is the city of Deir ez-Zor.

At the 2004 census, the district had a population of 492,434.

[1] The district of Deir ez-Zor is divided into seven subdistricts or nawāḥī (population as of 2004[1]):

This article about a location in Deir ez-Zor Governorate, Syria is a stub.