Mayfield is an unincorporated community in the central part of Scopus Township in Bollinger County, Missouri, United States, approximately 4.5 miles west of the Cape Girardeau County line.

[1][2] The community was located along a small tributary of the Little Whitewater Creek and Mayfield Creek flows past approximately three-quarters of a mile to the south.

Mayfield, who had established the post office in 1886.

[4] A number of post offices came and went over the years: 1882–1891, 1899–1909, 1912–1955.

This Bollinger County, Missouri state location article is a stub.