McN5652[1] is a molecule that can be radiolabeled and then used as a radioligand in positron emission tomography (PET) studies.

[2] The radioligand is used for molecular neuroimaging and for imaging of the lungs.

According to McNeil, McN5652 was among the strongest SRI ever reported at the time of its discovery (sub nM Ki).

Paroxetine was listed as 5-HT=0.44 nM, NA=20, and DA=460nM in the same paper by the same authors.

McN5652 and related structures have been analyzed for QSAR in terms of binding to the MAT receptor binding site.