Mecicobothrium is a genus of dwarf tarantulas first described by Eduardo Ladislao Holmberg in 1882.

The cephalic groove (fovea) is longitudinal.

The male palpal bulb lies in a long modified final joint.

The posterior lateral spinnerets are very long, with the last joint whiplike.

[3] As of July 2020[update], the genus contained only two species:[1]