Mecistocephalus simplex is a species of centipede in the Mecistocephalidae family.

It is endemic to Australia, and was first described in 1920 by American biologist Ralph Vary Chamberlin.

[1][2] The original description of this species is based on a specimen measuring 40 mm in length.

[1] The species occurs in coastal north-eastern Queensland.

[2] The centipedes are solitary terrestrial predators that inhabit plant litter and soil.