[2] The college served roughly 1,600 students, mainly from Western New York and Southern Ontario,[3] during its final years.

In May 2022, the Board of Regents of the New York State Department of Education approved Medaille College's request to be designated a university.

This training center for nuns and other vowed women who wanted to serve the church in education, laid the first foundations for what would later eventually become Medaille College.

"[9] In May 2021, Medaille was sanctioned by the American Association of University Professors for eliminating shared governance with the faculty during the early months of the COVID-19 pandemic.

[10] In 2022, Medaille and nearby Trocaire College signed a memorandum of understanding that set "in motion a cooperative agreement that would fulfill the missions of both institutions into the future.

Medaille was a charter member of the Allegheny Mountain Collegiate Conference, as an NCAA Division III school.