Megali Mantineia (Greek: Μεγάλη Μαντίνεια) is a mountain settlement in the municipal unit of Avia, Messenia, Greece.

In the mid 18th century, it was an important settlement in the area of Zarnata (Ζαρνάτα).

From the mid 19th century, a part of the population moved into the seaside areas including Palaiochora (now Avia), Archontiko and Akrogiali.

In 1914 Megali Mantineia became an independent community which included the new settlements.

In 1924 the seat of the community moved to the seaside village Palaiochora.