Meiotic drive

More simply, meiotic drive is when one copy of a gene is passed on to offspring more than the expected 50% of the time.

[1] The first report of meiotic drive came from Marcus Rhoades who in 1942 observed a violation of Mendelian segregation ratios for the R locus - a gene controlling the production of the purple pigment anthocyanin in maize kernels - in a maize line carrying abnormal chromosome 10 (Ab10).

For instance, the proposal that hybrid sterility (Haldane's rule) may arise from the divergent evolution of sex chromosome drivers and their suppressors.

[6] Early observations of mouse t-haplotypes by Mary Lyon described numerous genetic loci on chromosome 17 that suppress X-chromosome sex ratio distortion.

[11] Multiple species of fruit fly are known to have driving X chromosomes, of which the best-characterized are found in Drosophila simulans.