MaHaRam's knowledge of the Talmud and Poskim was such that he was invited to the rabbinate of Kraków in 1587, when he was not yet thirty years old.

He writes that he wanted to embarrass him in the synagogue of Lublin and to convene with the leaders of the communities to demote him from his position, but he decided not to because "perhaps it will be an honor for him that a person like me is occupied with someone like him".

From then on, the communal leaders decreed that the students could not tell one another of the new interpretation of the Rabbis and that whoever violated this ban would be expelled from the Yeshiva.

When the right opportunity came up, they grabbed one of the students of R' Shimon Wolf, beat him up and forced him to repeat the interpretation of his Rabbi.

The Maharsha gave a sermon on Shabbat night and convinced the community of Lublin to keep both of these Torah giants among them, and the controversy ended.

[5] Meir Einei Chachamim is his best known work, a "casuistic commentary" on the Talmud, Rashi, and Tosafot together.

It was published by his son Gedaliah and has since been printed in all principal editions of the Talmud under the heading "MaHaRam."

After his death, over 140 of the Halachic questions posed to him were published in a collection of responsa entitled Manhir Einei Chachamim.