Melcombe Regis was a station on the Portland Branch Railway in the English county of Dorset.

Opened in April 1909, it was sited at the north end of the bridge over Radipole Lake.

The branch junction was to the north of Weymouth station and faced Dorchester.

The last remains were removed in 2000 and the site is now under the relief road at the north end of Swannery Bridge near a car park.

This article about a railway station in South West England is a stub.