[1][2] The hospital places a large emphasis on innovation, and is the second-largest employer in the St. Joseph County, Indiana area.

[1][2] Clinical services include inpatient and outpatient surgery, heart and vascular, newborn intensive care, pediatrics, childbirth, children's therapy, cancer, rehabilitation, sleep disorders, sports medicine, radiology, bariatrics, occupational health and clinical research.

[6] In March 2011, Memorial Hospital purchased the inpatient assets of Madison Center, a local mental health facility, adding approximately 90 beds and starting an inpatient psychiatry program for both Adult and Pediatric patients in the new Memorial Epworth Center.

According to the Journal of Healthcare Management, "...hospitals are experiencing many of the same competitive problems that plague other industries, such as the lack of differentiated services, a shrinking operating margin, and shortage of talent.

The organization partnered with numerous businesses outside of healthcare including 3M, Dupont, IDEO, Land's End, Motorola, Steelcase, Walmart and Whirlpool to develop standards for managing an in-house innovation program.