Mesanerpeton is an extinct genus of four-limbed stem-tetrapod from the Mississippian (Tournaisian) of Scotland.

It contains a single species, Mesanerpeton woodi,[n 1] who based on a disarticulated specimen including a clavicle, vertebrae, and forelimb bones from the Ballagan Formation.

The vertebrae are poorly-ossified and similar to Crassigyrinus, but the forelimb was robust.

The shape and level of torsion present in the humerus are intermediate between Devonian stem-tetrapods and later Carboniferous tetrapods.

This transitional condition, and the associated rerouting of the brachial artery and median nerve, may indicate that Mesanerpeton had a higher stride length and more efficient locomotion on land compared to its predecessors.