Mesorhabditis acidophila is a species of nematode that has been discovered by Borgonie et al. [1] in 2010.

This species was first found in a cave called Cueva de Villa Luz in Tabasco, Mexico.

The cave was filled with approximately 32 subterranean springs that rise from the floor; some of them contain a high concentration of hydrogen sulfide (H2S).

When H2S and oxygen are absorbed by the water on the cave wall, sulfuric acid in high concentration is formed due to oxidation.

A phylogenetic tree shows more detailed information about the phylogeny of this species.